Hyperactivity of donor B cells after neonatal induction of lymphoid chimerism in mice.

Balb/c mice made chimaeric by neonatal injection of semi-allogeneic (A/J x Balb/c)F1 hybrid spleen cells develop anti-DNA and rheumatoid factor-like antibodies in the context of hypergammaglobulinaemia with marked elevation of IgG1 and IgE serum levels. Chimaeric mice also display increased levels o...

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Bibliographic Details
Main Authors: Goldman, M, Abramowicz, D, Lambert, P, Vandervorst, P, Bruyns, C, Toussaint, C
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541507/
https://ncbi.nlm.nih.gov/pubmed/3260841
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