Tolerogenic activity of polymerized type II collagen in preventing collagen-induced arthritis in rats.

Rats were exposed parenterally or pergastrically to polymerized type II collagen (POLCII) and became resistant to the subsequent induction of disease with arthritogenic type II collagen (CII) administered intradermally in Freund's incomplete adjuvant (FIA). POLCII was prepared by cross-linking...

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Bibliographic Details
Main Authors: Thompson, H S, Henderson, B, Spencer, J M, Hobbs, S M, Peppard, J V, Staines, N A
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541489/
https://ncbi.nlm.nih.gov/pubmed/3396219
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