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Neutrophil lysosomal degradation of human CRP: CRP-derived peptides modulate neutrophil function.

Hydrolysis of human C-reactive protein (CRP) at pH 4.5 and pH 7.4 with neutrophil-derived lysosomal enzymes yielded 10% trichloroacetic acid soluble peptides (Mr less than 14,000). These peptides inhibited neutrophil superoxide production, chemotaxis, degranulation and phagocytosis at 2 micrograms/m...

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Detalhes bibliográficos
Main Authors: Shephard, E G, Anderson, R, Beer, S M, Van Rensburg, C E, de Beer, F C
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541475/
https://ncbi.nlm.nih.gov/pubmed/3168329
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