T cell clones providing helper function for IgE synthesis release soluble factor(s) that induce IgE production in human B cells: possible role for interleukin 4 (IL-4).

We have previously demonstrated that a proportion of human T cell clones (TCC) derived from tonsil or peripheral blood (PB) of non-allergic donors, upon triggering with phytohaemagglutinin (PHA) or anti-CD3 monoclonal antibody (MoAb), were able to provide help for IgE synthesis in B cells from both...

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Bibliographic Details
Main Authors: Maggi, E, Del Prete, G F, Tiri, A, Macchia, D, Parronchi, P, Ricci, M, Romagnani, S
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541472/
https://ncbi.nlm.nih.gov/pubmed/2971487
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