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The activation of the C3b feedback cycle with human complement components. II. Using components of the alternative pathway.

The C3 convertase of the C3b feedback cycle was generated in the fluid phase from C3b and factors B and D. It was shown to be an effective decomplementing agent when reacted with human serum. Many of the effects observed were dependent on the operation of the feedback during the ongoing reaction. Ox...

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Main Authors: Mak, L W, Majewski, J, Lachmann, P J
Formato: Artigo
Idioma:Inglês
Publicado: 1977
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541114/
https://ncbi.nlm.nih.gov/pubmed/606443
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