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Intestinal trefoil factor confers colonic epithelial resistance to apoptosis

Intestinal trefoil factor (ITF) is an essential regulator of colonic epithelial restitution, the rapid migration of colonocytes over mucosal wounds. High levels of ITF are frequently present in colorectal cancers and derived cell lines. Mucosal restitution requires the detachment of epithelium from...

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Bibliographic Details
Main Authors: Taupin, D. R., Kinoshita, K., Podolsky, D. K.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC15411/
https://ncbi.nlm.nih.gov/pubmed/10639160
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