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IfkA, a presumptive eIF2α kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound size

BACKGROUND: The transition from growth to development in Dictyostelium is initiated by amino acid starvation of growing amobae. In other eukaryotes, a key sensor of amino acid starvation and mediator of the resulting physiological responses is the GCN2 protein, an eIF2α kinase. GCN2 downregulates th...

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Pubblicato in:BMC Dev Biol
Autori principali: Fang, Rui, Xiong, Yanhua, Singleton, Charles K
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-213X-3-3
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