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Mutational Analysis of the Carboxy-Terminal (YGX)(4) Repeat Domain of CpsD, an Autophosphorylating Tyrosine Kinase Required for Capsule Biosynthesis in Streptococcus pneumoniae

In Streptococcus pneumoniae, CpsB, CpsC, and CpsD are essential for encapsulation, and mutants containing deletions of cpsB, cpsC, or cpsD exhibit rough colony morphologies. CpsD is an autophosphorylating protein-tyrosine kinase, CpsC is required for CpsD tyrosine phosphorylation, and CpsB is a phos...

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Bibliografiske detaljer
Main Authors: Morona, Judy K., Morona, Renato, Miller, David C., Paton, James C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154072/
https://ncbi.nlm.nih.gov/pubmed/12730159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.10.3009-3019.2003
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