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Repair System for Noncanonical Purines in Escherichia coli

Exposure of Escherichia coli strains deficient in molybdopterin biosynthesis (moa) to the purine base N-6-hydroxylaminopurine (HAP) is mutagenic and toxic. We show that moa mutants exposed to HAP also exhibit elevated mutagenesis, a hyperrecombination phenotype, and increased SOS induction. The E. c...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Burgis, Nicholas E., Brucker, Jason J., Cunningham, Richard P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.3101-3110.2003
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