Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

The contribution of the aryl hydrocarbon receptor (AhR) in induction of a battery of xenobiotic-metabolizing enzymes has been studied extensively. However, no direct proof has been obtained that it plays a role in modulating carcinogenesis. To address the question of whether AhR is required for tumo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Shimizu, Yasuhito, Nakatsuru, Yoko, Ichinose, Masao, Takahashi, Yoshihisa, Kume, Haruki, Mimura, Junsei, Fujii-Kuriyama, Yoshiaki, Ishikawa, Takatoshi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.779
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