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Vesicular Stomatitis Viruses with Rearranged Genomes Have Altered Invasiveness and Neuropathogenesis in Mice

Transcription of vesicular stomatitis virus is controlled by the position of a gene relative to the single 3′ genomic promoter: promoter-proximal genes are transcribed at higher levels than those in more 5′ distal positions. In previous work, we generated viruses having rearranged gene orders. These...

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Udgivet i:J Virol
Principais autores: Flanagan, E. Brian, Schoeb, Trenton R., Wertz, Gail W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154046/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12719567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.10.5740-5748.2003
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