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Sindbis Virus Vectors Designed To Express a Foreign Protein as a Cleavable Component of the Viral Structural Polyprotein

Alphavirus-based expression vectors commonly use a duplicated 26S promoter to drive expression of a foreign gene. Here we describe an expression strategy in which the foreign sequences are linked to the gene encoding the 2A protease of foot-and-mouth disease virus and then inserted in frame between...

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Bibliografiske detaljer
Main Authors: Thomas, John M., Klimstra, William B., Ryman, Kate D., Heidner, Hans W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154044/
https://ncbi.nlm.nih.gov/pubmed/12719552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5598-5606.2003
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