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Maintenance of Gammaherpesvirus Latency Requires Viral Cyclin in the Absence of B Lymphocytes

Gammaherpesviruses establish a life-long chronic infection that is tightly controlled by the host immune response. We previously demonstrated that viruses lacking the gammaherpesvirus 68 (γHV68) viral cyclin (v-cyclin) exhibited a severe defect in reactivation from latency and persistent replication...

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Detalhes bibliográficos
Main Authors: van Dyk, Linda F., Virgin IV, Herbert W., Speck, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153990/
https://ncbi.nlm.nih.gov/pubmed/12692214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5118-5126.2003
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