Genome Delivery and Ion Channel Properties Are Altered in VP4 Mutants of Poliovirus

During entry into host cells, poliovirus undergoes a receptor-mediated conformational transition to form 135S particles with irreversible exposure of VP4 capsid sequences and VP1 N termini. To understand the role of VP4 during virus entry, the fate of VP4 during infection by site-specific mutants at...

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Bibliographic Details
Main Authors: Danthi, Pranav, Tosteson, Magdalena, Li, Qi-han, Chow, Marie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC153979/
https://ncbi.nlm.nih.gov/pubmed/12692228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5266-5274.2003
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