Attenuated Salmonella enterica Serovar Typhi and Shigella flexneri 2a Strains Mucosally Deliver DNA Vaccines Encoding Measles Virus Hemagglutinin, Inducing Specific Immune Responses and Protection in Cotton Rats

Measles remains a leading cause of child mortality in developing countries. Residual maternal measles antibodies and immunologic immaturity dampen immunogenicity of the current vaccine in young infants. Because cotton rat respiratory tract is susceptible to measles virus (MV) replication after intra...

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Detalhes bibliográficos
Main Authors: Pasetti, Marcela F., Barry, Eileen M., Losonsky, Genevieve, Singh, Mahender, Medina-Moreno, Sandra M., Polo, John M., Ulmer, Jeffrey, Robinson, Harriet, Sztein, Marcelo B., Levine, Myron M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153971/
https://ncbi.nlm.nih.gov/pubmed/12692223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5209-5217.2003
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