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Role of Transcription Factor T-bet Expression by CD4(+) Cells in Gastritis Due to Helicobacter pylori in Mice

Gastritis due to Helicobacter pylori is induced by a Th1-mediated response that is CD4 cell and gamma interferon (IFN-γ) dependent. T-bet is a transcription factor that directs differentiation of and IFN-γ secretion by CD4(+) Th1 T cells. The goal of this study was to use two mouse models to elucida...

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Detalhes bibliográficos
Main Authors: Eaton, Kathryn A., Benson, Lucy H., Haeger, Jennifer, Gray, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539619/
https://ncbi.nlm.nih.gov/pubmed/16861655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01887-05
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