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Murine Model of Infection by Tropheryma whipplei

We developed an animal model reproducing several aspects of Whipple's disease. Immunocompetent mice were persistently infected with Tropheryma whipplei, its etiological agent, and developed liver granulomas. SCID mice were infected similarly but did not develop tissue lesions. The delayed clear...

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Bibliographic Details
Main Authors: Genot, Séverine, Stein, Andreas, Lepidi, Hubert, Ihrig, Melanie, Raoult, Didier, Mege, Jean-Louis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539611/
https://ncbi.nlm.nih.gov/pubmed/16861681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00283-06
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