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ReadOut: structure-based calculation of direct and indirect readout energies and specificities for protein–DNA recognition
Protein–DNA interactions play a central role in regulatory processes at the genetic level. DNA-binding proteins recognize their targets by direct base–amino acid interactions and indirect conformational energy contribution from DNA deformations and elasticity. Knowledge-based approach based on the s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1538882/ https://ncbi.nlm.nih.gov/pubmed/16844974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl104 |
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