The pseudo-mitochondrial genome influences mistakes in heteroplasmy interpretation

BACKGROUND: Nuclear mitochondrial pseudogenes (numts) are a potential source of contamination during mitochondrial DNA PCR amplification. This possibility warrants careful experimental design and cautious interpretation of heteroplasmic results. RESULTS: Here we report the cloning and sequencing of...

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Autori principali: Parr, Ryan L, Maki, Jennifer, Reguly, Brian, Dakubo, Gabriel D, Aguirre, Andrea, Wittock, Roy, Robinson, Kerry, Jakupciak, John P, Thayer, Robert E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538596/
https://ncbi.nlm.nih.gov/pubmed/16859552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-185
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