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Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1
In Saccharomyces cerevisiae, the Tap42–phosphatase complexes are major targets of the Tor kinases in the rapamycin-sensitive signaling pathway. The immunosuppressive agent, rapamycin, induces a prompt activation of the Tap42-associated phosphatases, which is vitally important in Tor-mediated transcr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1538558/ https://ncbi.nlm.nih.gov/pubmed/16874307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601239 |
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