Intersectin-1L nucleotide exchange factor regulates secretory granule exocytosis by activating Cdc42

Rho GTPases are key regulators of the actin cytoskeleton in membrane trafficking events. We previously reported that Cdc42 facilitates exocytosis in neuroendocrine cells by stimulating actin assembly at docking sites for secretory granules. These findings raise the question of the mechanism activati...

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Detaylı Bibliyografya
Asıl Yazarlar: Malacombe, Magali, Ceridono, Mara, Calco, Valérie, Chasserot-Golaz, Sylvette, McPherson, Peter S, Bader, Marie-France, Gasman, Stéphane
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538555/
https://ncbi.nlm.nih.gov/pubmed/16874303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601247
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