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The cofactors required by C3 nephritic factor to generate a C3 convertase in vitro.

The mechanisms by which a C3 convertase is generated by C3 nephritic factor (NeF) were investigated using purified NeF, C3, C3b, factor B and factor D of the alternative pathway of complement activation. NeF could generate a C3 convertase with C3 and B in the absence of D, and without cleavage of B....

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Dettagli Bibliografici
Autori principali: Amos, N, Sissons, J G, Girard, J F, Lachmann, P J, Peters, D K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1976
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538539/
https://ncbi.nlm.nih.gov/pubmed/939051
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