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Proteolysis of human IgG by human polymorphonuclear leucocyte elastase produces an Fc fragment with in vitro biological activity.

The Fc fragment derived by proteolysis of human IgG by human polymorphonuclear leucocyte (PMN) elastase was tested for in vitro biological activity. This fragment could attach to the specific IgG receptor of Staphylococcus aureus Cowan I cells (protein A) and could be eluted from the cells with diss...

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Autori principali: Prince, H E, Folds, J D, Spitznagel, J K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1537657/
https://ncbi.nlm.nih.gov/pubmed/487653
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