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Mechanisms of TNF-α– and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis

Psoriatic arthritis (PsA) is an inflammatory joint disease characterized by extensive bone resorption. The mechanisms underlying this matrix loss have not been elucidated. We report here that blood samples from PsA patients, particularly those with bone erosions visible on plain radiographs, exhibit...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Ritchlin, Christopher T., Haas-Smith, Sally A., Li, Ping, Hicks, David G., Schwarz, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12639988/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16069
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