The hepatitis C virus internal ribosome entry site facilitates efficient protein synthesis in blood vessel endothelium during tumour angiogenesis

The development of gene delivery systems for therapeutic use involves vectors (often retrovirus or adenovirus) which typically encode one target protein, but the use of internal ribosome entry sites (IRES) can confer the ability to express more than one protein from bi- or polycistronic mRNAs. IRES...

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Hlavní autoři: Chung, Grace T. Y., Yamada, Yoshihiro, Pannell, Richard, Forster, Alan, Rabbitts, Terence H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
NAR Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC153758/
https://ncbi.nlm.nih.gov/pubmed/12682381
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