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Effect of methotrexate on the response of rat lymphocytes to phytohaemagglutinin

The proliferative responses of rat peripheral blood lymphocytes (PBL) and spleen cells to phytohaemagglutinin (PHA) were studied following either single or multiple (daily for 4 days) doses of methotrexate (MTX). Lymphopenia developed 72 hr after a single dose of MTX. Multiple doses of MTX caused a...

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Autors principals: Mansour, A., Henderson, Julia A., Nelson, D. S.
Format: Artigo
Idioma:Inglês
Publicat: 1978
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1537544/
https://ncbi.nlm.nih.gov/pubmed/743808
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