Phosphorylation of deoxyguanosine by B and T lymphocytes: evidence against selective trapping of deoxyguanosine by T lymphocytes in purine nucleoside phosphorylase deficiency.

T and B lymphocytes from blood and tonsils, as well as T and B lymphoid cell lines, phosphorylate deoxyguanosine which is probably the major toxic metabolite in purine nucleoside phosphorylase (PNP) deficiency. T and B cells also have similar activities of purine nucleoside phosphorylase. These find...

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Bibliographic Details
Main Authors: North, M E, Newton, C A, Webster, A D
Format: Artigo
Language:Inglês
Published: 1980
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1537153/
https://ncbi.nlm.nih.gov/pubmed/6783354
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