Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis

When challenged by DNA-damaging agents, Escherichia coli cells respond by inducing the SOS stress response, which leads to an increase in mutation frequency by two mechanisms: translesion replication, a process that causes mutations because of misinsertion opposite the lesions, and an inducible muta...

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Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Maor-Shoshani, Ayelet, Reuven, Nina Bacher, Tomer, Guy, Livneh, Zvi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2000
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.565
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