The Chediak-Higashi gene in humans. III. Studies on the mechanisms of NK impairment.

Lymphocytes from six Chediak-Higashi (CH) patients were markedly depressed in their ability to lyse tumour cell targets in both 51Cr release and single cell cytotoxicity assays. The frequency of lymphocytes bearing the OKM1 marker and the frequency of T3+, T4+, T8+, Ia+, Mo1+, Mo2+ and B1+ cells was...

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Detalhes bibliográficos
Main Authors: Roder, J C, Todd, R F, Rubin, P, Haliotis, T, Helfand, S L, Werkmeister, J, Pross, H F, Boxer, L A, Schlossman, S F, Fauci, A S
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536889/
https://ncbi.nlm.nih.gov/pubmed/6839545
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