Action of deoxycoformycin on human T cell colonies in vitro.

The potent adenosine deaminase inhibitor, deoxycoformycin (dCF), is currently under evaluation in the treatment of lymphoid malignancy. We show that dCF inhibits the growth in soft agar of T cell colonies from PHA stimulated human peripheral blood lymphocytes. In contrast to previous attempts to dev...

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Main Authors: Colledge, N R, Krajewski, A S, Smyth, J F, Wyllie, A H
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536861/
https://ncbi.nlm.nih.gov/pubmed/6983406
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