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Role of sulphydryl groups in T lymphocyte-mediated cytotoxicity.

The role of thiols in T cell-mediated cytotoxicity was investigated by studying the thiols of the target cell and cytotoxic cell separately. Agents which protect the reduced thiols of the target cell inhibit their lysis by the cytotoxic T cells; thiol reactive reagents may be directly toxic to the t...

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Bibliographic Details
Main Authors: Thorne, K J, Free, J, Franks, D
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536835/
https://ncbi.nlm.nih.gov/pubmed/6984671
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