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Prostaglandins and prostaglandin synthetase inhibitors regulate the synthesis of complement components by human monocytes.

The addition of prostaglandins E2 (PGE2), PGD2, PGI2, 6-keto PGF1 alpha and thromboxane B2 (TXB2) to human monocyte cultures, inhibited the production of the second component of complement (C2). PGF2 alpha did not significantly affect C2 production. As the former compounds, but not the latter increa...

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Bibliographic Details
Main Authors: Lappin, D F, Whaley, K
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536723/
https://ncbi.nlm.nih.gov/pubmed/6816495
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