Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: Intrinsic stability predicts lifelong persistence

Viral replication and latently infected cellular reservoirs persist in HIV-infected patients achieving undetectable plasma virus levels with potent antiretroviral therapy. We exploited a predictable drug resistance mutation in the HIV reverse transcriptase to label and track cells infected during de...

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Détails bibliographiques
Auteurs principaux: Strain, M. C., Günthard, H. F., Havlir, D. V., Ignacio, C. C., Smith, D. M., Leigh-Brown, A. J., Macaranas, T. R., Lam, R. Y., Daly, O. A., Fischer, M., Opravil, M., Levine, H., Bacheler, L., Spina, C. A., Richman, D. D., Wong, J. K.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC153639/
https://ncbi.nlm.nih.gov/pubmed/12684537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736332100
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