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Erythrocyte-binding antigen 175 mediates invasion in Plasmodium falciparum utilizing sialic acid-dependent and -independent pathways

The Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175) is a ligand for merozoite invasion into human erythrocytes that binds to glycophorin A in a sialic acid-dependent manner. P. falciparum strain W2mef depends on sialic acid for invasion of erythrocytes, whereas 3D7 is sialic acid-ind...

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Bibliografiske detaljer
Main Authors: Duraisingh, Manoj T., Maier, Alexander G., Triglia, Tony, Cowman, Alan F.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153635/
https://ncbi.nlm.nih.gov/pubmed/12672957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730883100
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