Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis

Plaque angiogenesis promotes the growth of atheromas, but the functions of plaque capillaries are not fully determined. Neovascularization may act as a conduit for the entry of leukocytes into sites of chronic inflammation. We observe vasa vasorum density correlates highly with the extent of inflamm...

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Bibliographic Details
Main Authors: Moulton, Karen S., Vakili, Khashayar, Zurakowski, David, Soliman, Mohsin, Butterfield, Catherine, Sylvin, Erik, Lo, Kin-Ming, Gillies, Stephen, Javaherian, Kashi, Folkman, Judah
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC153625/
https://ncbi.nlm.nih.gov/pubmed/12682294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730843100
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