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Studies of complement activation and IgG subclass restriction of anti-thyroglobulin.

Using a sensitive radioimmunoassay, it was demonstrated that autoantibodies to human thyroglobulin (hTg) did not activate complement upon interaction with solid phase adsorbed hTg. Since IgG4 immunoglobulins do not activate complement, we studied sera containing large amounts of anti-thyroglobulin (...

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Detalles Bibliográficos
Main Authors: Adler, T R, Beall, G N, Curd, J G, Heiner, D C, Sabharwal, U K
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536243/
https://ncbi.nlm.nih.gov/pubmed/6733975
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