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Epstein–Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction

To assess the impact of the germinal center (GC) reaction on viral spread in Epstein–Barr virus (EBV) infection, we isolated EBV(+) GC B cells from the tonsils of two infectious mononucleosis patients, sequenced their rearranged V genes, and determined expression of the EBV latency genes EBV nuclear...

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Main Authors: Kurth, Julia, Hansmann, Martin-Leo, Rajewsky, Klaus, Küppers, Ralf
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC153624/
https://ncbi.nlm.nih.gov/pubmed/12665622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2627966100
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