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Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus

The candidate tumor-suppressor gene hyaluronidase 2 (HYAL2) encodes a glycosylphosphatidylinositol-anchored cell-surface protein that serves as an entry receptor for jaagsiekte sheep retrovirus, a virus that causes contagious lung cancer in sheep that is morphologically similar to human bronchioloal...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Danilkovitch-Miagkova, Alla, Duh, Fuh-Mei, Kuzmin, Igor, Angeloni, Debora, Liu, Shan-Lu, Miller, A. Dusty, Lerman, Michael I.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12676986/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0837136100
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