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In vitro hyporeactivity to alpha-interferon in children with severe combined immunodeficiency disease.

Interferon (IFN) treatment of peripheral blood mononuclear cells from seven children with severe combined immunodeficiency (SCID) failed, with one exception, to induce the IFN-dependent enzyme, 2-5A synthetase or enhance natural killer cell activity. In one patient this hyporeactivity was demonstrat...

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Detalhes bibliográficos
Main Authors: Williams, B R, Read, S E, Gelfand, E W
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535959/
https://ncbi.nlm.nih.gov/pubmed/6609035
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