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Effect of DNA size and strandedness on the in vivo clearance and organ localization of DNA.

DNA-anti-DNA immune complexes play a major role in the pathogenesis of SLE. Evidence suggests that the DNA contained within these complexes, as well as free circulating DNA, is of small molecular weight and predominantly double stranded. Previous studies have shown that large DNA is cleared from cir...

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Detalhes bibliográficos
Main Authors: Emlen, W, Mannik, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535948/
https://ncbi.nlm.nih.gov/pubmed/6609032
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