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Effect of thymosin on glucocorticoid receptor activity and glucocorticoid sensitivity of human thymocytes.

Incubation with thymosin fraction 5, (TMS F5 at 300 micrograms/ml) a partially purified thymic factor, reduced the steroid binding activity of human infant thymocytes from 9.6 +/- 2.1 fmole/ml to 5.0 +/- 2.0 fmole/ml. The glucocorticoid receptor activity in normal infant thymocytes was found to be 2...

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Autors principals: Ma, D D, Ho, A H, Hoffbrand, A V
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535816/
https://ncbi.nlm.nih.gov/pubmed/6607790
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