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Quantification of cross-reactive idiotype-positive rheumatoid factor produced in autoimmune rheumatic diseases. An indicator of clonality and B cell proliferative mechanisms.

The aetiology of sustained autoantibody production in human autoimmune diseases is unknown. Evidence for structural similarities and common clonal origin among autoantibodies have been demonstrated through the expression of cross-reactive idiotype (CRI). In the present study we use four monoclonal a...

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Detalhes bibliográficos
Main Authors: Shokri, F, Mageed, R A, Kitas, G D, Katsikis, P, Moutsopoulos, H M, Jefferis, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535709/
https://ncbi.nlm.nih.gov/pubmed/2070558
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