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Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes

Mature T cell activation and selection of immature T cells (thymocytes) are both initiated by binding of T cell receptor (TCR) molecules on the surface of T cells to MHC peptide (MHCp) molecules on the surface of antigen-presenting cells. Recent experiments have shown that the spatial pattern of rec...

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Autors principals: Lee, Sung-Joo E., Hori, Yuko, Chakraborty, Arup K.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153563/
https://ncbi.nlm.nih.gov/pubmed/12671067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0630563100
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