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Inhibition by FK506 of established lesions of collagen-induced arthritis in rats.

We investigated the superior potency of the immunosuppressive agent FK506 on collagen-induced arthritis in rats. In our initial studies, we demonstrated that only one shot administration of FK506 at a dose of 10 mg/kg on the same day as type II collagen immunization suppressed the incidence of arthr...

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Bibliografiske detaljer
Main Authors: Arita, C, Hotokebuchi, T, Miyahara, H, Arai, K, Sugioka, Y, Kaibara, N
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535516/
https://ncbi.nlm.nih.gov/pubmed/1702374
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