A T cell receptor beta chain polymorphism is associated with patients developing insulin-dependent diabetes after the age of 20 years.

We have studied the BglII polymorphism near the T cell receptor beta chain constant region (TcR-C beta) gene, HLA-DR genotypes and certain autoimmune features in 102 patients with type I (insulin-dependent) diabetes. There was a significant decrease in the frequency of the 1:1 genotype (P = 0.008) a...

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Detalhes bibliográficos
Main Authors: McMillan, S A, Graham, C A, Hart, P J, Hadden, D R, McNeill, T A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535501/
https://ncbi.nlm.nih.gov/pubmed/1979939
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