Formation of subepithelial dense deposits in rats induced by a monoclonal antibody against the glomerular cell surface antigen.

We developed a monoclonal antibody, H5H3, of IgG1 subclass by hybridization technique using spleen cells of mice immunized with plasma membrane fraction of isolated rat glomeruli. H5H3 recognized main bands at about 220 kD by immuno-overlay technique and bound to the glomerulus as well as brush bord...

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Huvudupphovsmän: Nishikawa, K, Fukatsu, A, Tamai, H, Suzuki, N, Ito, Y, Sakamoto, N, Matsuo, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535473/
https://ncbi.nlm.nih.gov/pubmed/1988221
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