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An inhibitor of the toxicity of tumour necrosis factor in the serum of patients with sarcoidosis, tuberculosis and Crohn's disease.

The activated macrophages present in the T cell-dependent granulomata of sarcoidosis and tuberculosis are primed for enhanced release of cytokines including tumour necrosis factor (TNF or cachectin). Release of this cytokine can induce an acute-phase response, fever, and necrosis in suitably prepare...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Foley, N, Lambert, C, McNicol, M, Johnson, N, Rook, G A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535197/
https://ncbi.nlm.nih.gov/pubmed/1695561
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