Anti-heparan sulphate reactivity in sera from patients with systemic lupus erythematosus with renal or non-renal manifestations.

Previously, we have shown that anti-DNA can bind to heparan sulphate (HS), a constituent of the glomerular basement membrane (GBM). We hypothesized that binding of anti-DNA to HS in the GBM plays a role in the onset of systemic lupus erythematosus (SLE) nephritis. To test this hypothesis we measured...

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Autors principals: Termaat, R M, Brinkman, K, Nossent, J C, Swaak, A J, Smeenk, R J, Berden, J H
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535136/
https://ncbi.nlm.nih.gov/pubmed/2242607
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