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Occurrence of two germline-related rheumatoid factor idiotypes in rheumatoid arthritis and in non-rheumatoid seropositive individuals.

Human rheumatoid factor (RF) paraproteins express two distinct light chain cross-reactive idiotypes defined by the monoclonal antibodies 17.109 and 6B6.6. These germline gene-related cross-reactive idiotypes are both carried on VK3 light chains and are each present on about one-third of IgM RF parap...

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Bibliographic Details
Main Authors: Kouri, T, Crowley, J, Aho, K, Palosuo, T, Isomäki, H, von Essen, R, Heliövaara, M, Carson, D, Vaughan, J H
Format: Artigo
Language:Inglês
Published: 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535133/
https://ncbi.nlm.nih.gov/pubmed/2122932
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