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Antibody binding and inhibition of pyruvate dehydrogenase (PDH) in sera from patients with primary biliary cirrhosis.

Autoantibodies reactive against mitochondria which are present in sera from patients with primary biliary cirrhosis (PBC) have been shown to bind to the lipoamide acetyltransferase moiety (E2) of the pyruvate dehydrogenase enzyme complex (PDH). This newly described antigen has been shown to be ident...

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Bibliografische gegevens
Hoofdauteur: Sundin, U
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535059/
https://ncbi.nlm.nih.gov/pubmed/2387091
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